5% dextrose solution: The dose of Dextrose infusion is variable. It is dependent on individual patient requirements. For 5% dextrose solution, the dose frequently ranges from 500 to 1000 ml. The maximum rate of infusion that will not cause glycosuria is 0.5 g/kg/hour. About 95% is retained when the rate is 0.8 g/kg/hr. the maximum rate of glucose utilization is about 800 mg per kg body weight per hour.

25% dextrose solution: The volume and rate of infusion of dextrose solution will depend upon the requirements of the individual patient and the judgment of the physician. The maximum rate at which dextrose can be infused without producing glycosuria is 0.5 g/kg/hr. The usual recommended flow rate for adult is 10-35 drops per minute infused intravenously. It should not be administered by SC or IM route. 25% dextrose solution should be infused through the largest available peripheral vein.

• Check infusion set and infusion solution prior to use.
• Pull moderately to tear off the protective cover of the Eurocap.
• Hold lightly the Eurocap but not the bottle body.
• Open the flow regulator fully and hold the giving set on the top white area, but not the memorane venting region.
• Insert the spike of the administration set to the Eurocap and fit the connector of the administration set firmly to the needle.
• Gradually allow the fluid to flow down to the needletip and close.
• Remove the protective cover of the needle.
• Locate the venpuncture site and clean the site with an antiseptic solution, and then insert the needle.
• Securely tape the puncture site.
• Securely tape the wings and tubing
• Start infusion while adjusting drip speed.

• severe burning, pain, or swelling around the IV needle;
• warmth, redness, oozing, or bleeding where the IV was placed;
• fever, ongoing cough;
• high blood sugar, headache, trouble concentrating, memory problems, weakness, feeling unsteady, hallucinations, fainting, seizure, shallow breathing or breathing that stops;
• low potassium or anxiety, sweating, pale skin, severe shortness of breath, wheezing, pain, fast or uneven heart rate.

Serum glucose concentration should be carefully monitored. Concurrent use of insulin may be needed in case of diabetic patients. Dextrose solution should not be mixed with whole blood as haemolysis and clumping may occur. Infusion of fluid should be immediately discontinued if rigor arises for any reasons during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.

Take special care with dextrose. Check with your doctor before taking this medicine if: You should not use this medication if you are allergic to dextrose.

To make sure you can safely use dextrose 5% in water, tell your doctor if you have any of these other conditions:

• diabetes;
• breathing problems;
• an electrolyte imbalance (such as low levels of potassium in your blood);
• kidney or liver disease;
• any allergy to foods or medicines; or
• if you receive regular blood transfusions.